Phospho-IL3R(Y766) Antibody Blocking peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 1439
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: CSF2RB
Other Names: Cytokine receptor common subunit beta, CDw131, GM-CSF/IL-3/IL-5 receptor common beta subunit, CD131, CSF2RB, IL3RB, IL5RB
Availability: 2 weeks
Bio Background: IL3R (also known as CSF2RB) is a common beta chain of the high affinity receptor for IL-3, IL-5 and GM-CSF. Defective IL3R has been reported to be associated with protein alveolar proteinosis (PAP). PAP is an autosomal recessive fatal respiratory disease.
Bio References: Murphy, J.M., et al., J. Biol. Chem. 279(25):26500-26508 (2004).McClure, B.J., et al., Blood 101(4):1308-1315 (2003).Scibek, J.J., et al., Anal. Biochem. 307(2):258-265 (2002).Blake, T.J., et al., J. Leukoc. Biol. 72(6):1246-1255 (2002).Evans, C.A., et al., Blood 100(9):3164-3174 (2002).
Primary Accession: P32927
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP3133a was selected from the region of human Phospho-IL3R-Y766. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.