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Human Regulator of G-protein Signaling 2, RGS2 ELISA Kit

Bioassay Technology Laboratory


Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11063746, PubMed:19478087). It is involved in the negative regulation of the angiotensin-activated signaling pathway (PubMed:28784619). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein (PubMed:19736320).


  • GeneID: 5997
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 24,382
  • Synonyms: Cell growth-inhibiting gene 31 protein;G0/G1 switch regulatory protein 8;G0S8;Regulator of G-protein signaling 2;RGS2
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: RGS2
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 8.96ng/L
  • Target Protein: RGS2
  • Detection Range: 20-3500ng/L
  • Full Product Name: Regulator of G-protein signaling 2
  • Standard Solution: 4000ng/L
  • UniProt Accession: P41220