E6074Hu
Human Regulator of G-protein Signaling 2, RGS2 ELISA Kit
Bioassay Technology Laboratory
DESCRIPTION
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11063746, PubMed:19478087).
It is involved in the negative regulation of the angiotensin-activated signaling pathway (PubMed:28784619).
Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity).
Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein (PubMed:19736320).
DETAILS
- GeneID: 5997
- Species: Human
- Storage: 2-8ºC
- MASS(Da): 24,382
- Synonyms: Cell growth-inhibiting gene 31 protein;G0/G1 switch regulatory protein 8;G0S8;Regulator of G-protein signaling 2;RGS2
- Assay Time: 1h 30m
- Assay Type: Sandwich
- Gene Names: RGS2
- Reactivity: Human
- Sample Type: Serum, plasma, cell culture supernates
- Sensitivity: 8.96ng/L
- Target Protein: RGS2
- Detection Range: 20-3500ng/L
- Full Product Name: Regulator of G-protein signaling 2
- Standard Solution: 4000ng/L
- UniProt Accession: P41220