14537
Scientist.com Supplier
PPADS (sodium salt)
Cayman Chemical
DESCRIPTION:
A non-selective P2 purinergic antagonist that blocks recombinant P2X1-5 (IC50s = 1-2.6 μM), native P2Y2-like (IC50 = ~0.9 mM), and recombinant P2Y4 (IC50 = ~15 mM) receptors; produces neuroprotective effects in an ischemia model with permanent middle cerebral artery occlusion in spontaneously hypertensive rats
DETAILS
- Inchi: InChI=1S/C14H14N3O12PS2.4Na/c1-7-13(19)9(5-18)10(6-29-30(20,21)22)14(15-7)17-16-11-3-2-8(31(23,24)25)4-12(11)32(26,27)28;;;;/h2-5,19H,6H2,1H3,(H2,20,21,22)(H,23,24,25)(H,26,27,28);;;;/q;4*+1/p-4/b17-16+;;;;
- Purity: ≥95%
- Raptas: Product Type|Biochemicals|Ion Channel Modulation|Blockers||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Cardiovascular System|Cardiovascular Diseases|Stroke||Research Area|Neuroscience|Neuroprotection|Ischemia
- Smiles: [H]C(C1=C(COP([O-])([O-])=O)C(/N=N/C2=C(S([O-])(=O)=O)C=C(S([O-])(=O)=O)C=C2)=NC(C)=C1O)=O.[Na+].[Na+].[Na+].[Na+]
- Inchikey: KURWUCJJNVPCHT-PGXCWKBOSA-J
- Cas Number: 192575-19-2
- Formulation: A solid
- Storage Temp: -20
- Shipping Temp: -20
- Formula Markup: C14H10N3O12PS2 • 4Na
- Formula Weight: 599.3
- Shelf Life Days: 1460