Mut-16 Antibody (Center) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 172873
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: O62011
Availability: 2 weeks
Bio Background: Mut-16 encodes a glutamine/asparagine (Q/N)-rich domain-containing protein that lacks obvious homologs outside of other nematode species; MUT-16 activity is required for RNA-mediated interference (RNAi), transgene silencing in germ-line and somatic tissues, and for maintaining low levels of transposon mobilization; MUT-16 is thus predicted to play a role in chromatin organization and/or regulation of gene expression.
Bio References: Kennedy S, et al. 2004. Nature 427:645-649.Kim JK, et al. 2005. Science 308:1164-1167.Robert VJP, et al. 2005. Genes Dev 19:782-787.Sijen T, et al. 2003. Nature 426:310-314.Vastenhouw NL, et al. 2003. Current Biology 13:1311-1316.
Primary Accession: O62011
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP1960c was selected from the Center region of human Mut-16. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.