DESCRIPTION

• Category: REAGENTS
• Keywords: T8, Leu2, flow cytometry antibody, flow cytometry antibodies, facs antibody, primary antibody, monoclonal antibody, anti-human antibody, Anti human, anti human antibody anti-CD8, CD8, anti CD8, SK1, Clone SK1, blue laser Antibody, CD14 blue, conjugated antibody, conjugated flow cytometry antibody, CD8 antibody, T4, Immunoglobulin, CD Marker, CD Markers, CD Antigen, PE CD8, PE
• Paragraph 1: The clone SK1 specifically binds with a 32-34kDa type I transmembrane glycoprotein of human cells commonly known as CD8a.  It is a member of immunoglobulin superfamily.  The CD8? forms either a homodimer (2 alpha chains) or a heterodimer with CD8? and is expressed on the surface of cytotoxic T cells, and sub-sets of NK cells, cortical thymocytes, and also on some dendritic cells. CD8 functions as a co-receptor for T cell receptor and specifically binds to class I MHC for antigen recognition and T cell activation. It has the cross-reactive binding affinity with the CD8 cell surface antigen expressing in several non-human primates, including Baboon, Chimpanzee, Cynomolgus and Rhesus.
• Paragraph 2: Each lot of these antibodies has been pre-titrated and tested by flow cytometric analysis of human PBMCs such that 0.5µg (unconjugated, Biotin) or 5µl (conjugated) of these products are sufficient for staining 1 million cells in a 100µl staining volume or 100µl of whole blood. It is recommended to titrate antibody reactivity empirically for optimal performance. Do you need an antibody for an antigen you don't see on our website? Do you need a different conjugation than what we have listed? We have a wide selection of antigens with a variety of conjugations available. Please reach out to us at support@geneseesci.com.
• Bullet Point 1: CD8a is a 32-34 kD type I glycoprotein
• Bullet Point 2: CD8 is known as T8 and Leu2
• Bullet Point 3: Highly specific and little to no cross reactivity to ensure accurate, reproducible results in Flow Cytometry
• Bullet Point 4: >90% pure tested via polyacrylamide gel electrophoresis (PAGE)
• Bullet Point 5: More conjugations and unit sizes available. Contact us at support@geneseesci.com to inquire.
• Manufacturer Sku: 110925