BRWD2 Antibody (Center) Blocking peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 55717
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: WDR11
Other Names: WD repeat-containing protein 11, Bromodomain and WD repeat-containing protein 2, WD repeat-containing protein 15, WDR11, BRWD2, KIAA1351, WDR15
Availability: 2 weeks
Bio Background: WDR11 is a member of the WD repeat proteinfamily. WD repeats are minimally conserved regions of approximately40 amino acids typically bracketed by gly-his and trp-asp (GH-WD),which may facilitate formation of heterotrimeric or multiproteincomplexes. Members of this family are involved in a variety ofcellular processes, including cell cycle progression, signaltransduction, apoptosis, and gene regulation. This gene is locatedin the chromosome 10q25-26 region, which is frequently deleted ingliomas and tumors of other tissues, and is disrupted by thet(10;19) translocation rearrangement in glioblastoma cells. Thegene location suggests that it is a candidate gene for the tumorsuppressor locus.
Bio References: Katoh, M., et al. Int. J. Mol. Med. 11(5):579-583(2003)Katoh, M., et al. Int. J. Oncol. 22(5):1155-1159(2003)Chernova, O.B., et al. Oncogene 20(38):5378-5392(2001)
Other Accession: NP_060587.8
Primary Accession: Q9BZH6