The Silica-C™ HPLC Columns are made with Cogent TYPE-C™ Silica, and provide unique Selectivity due to its surface chemistry (especially in Normal Phase HPLC) compared to standard silica, This Silica Hydride Phase is not modified and therefore has no end-capping or organic ligands.Chosen for analyzing compounds that are not soluble in Water including but not limited to: lipids, peptides, proteins, oligonucleotides and other compounds that require non polar solvents.Faster Equilibration than other Silica ColumnsNo need to control Moisture in Mobile Phase SolventsRobust Column LifetimesThis size column provides similar run times as a 4.6mm ID column, but uses much less mobile phase, with lower flow rates. No special equipment is needed for this column to save solvent use