BP6503a
IL1RN Antibody (Center) Blocking Peptide
Abcepta
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DETAILS
- Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
- Gene Id: 3557
- Category: Peptides; Blocking Peptides
- Subtitle: Synthetic peptide
- Gene Name: IL1RN
- Other Names: Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, ICIL-1RA, IL1 inhibitor, Anakinra, IL1RN, IL1F3, IL1RA
- Availability: 2 weeks
- Bio Background: The protein is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. A polymorphism of its gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer.
- Bio References: Kumar,S., Biochem. Biophys. Res. Commun. 387 (3), 456-460 (2009)Rechcinski,T., Kardiol Pol 67 (6), 601-610 (2009)
- Primary Accession: P18510
- Targetspecificity: The synthetic peptide sequence used to generate the antibody AP6503a was selected from the Center region of human IL1RN. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.