79115
JAK2 (V617F) (JH1, JH2 Domain), GST-Tag, Avi-Tag, Biotin-Labeled (Dephosphorylated) Recombinant
BPS Bioscience
Image
Image
DESCRIPTION
Human Jak2 with V617F mutation, GenBank Accession No. NM_004972, a.a. 513-1132 (end), with N-terminal GST tag, C-terminal Avi-Tag, expressed in a HEK293 cell expression system and enzymatically Biotin-labeled using AviTag™ technology.
DETAILS
- Aa: 513-1132 (end)
- Mw: 100 kDa
- Tags: h N-terminal GST tag, C-terminal Avi-Tag
- Format: Aqueous buffer solution
- Genbank: NM_004972
- Species: Human
- Uniprot: O60674
- Shiptemp: -80°C (dry ice)
- Synonyms: JAK2, Janus kinase-2, Just Another Kinase 2, V617F
- Warnings: Avoid freeze/thaw cycles.
- Category: Kinase/Kinase Receptor Tyrosine
- References: 1. Tono, C., et al., Leukemia. 2005; 19(10): 1843-1844. 2. Goerttler, P.S., et al., Blood. 2005; 106(8): 2862-2864.
- Description: Human Jak2 with V617F mutation, GenBank Accession No. NM_004972, a.a. 513-1132 (end), with N-terminal GST tag, C-terminal Avi-Tag, expressed in a HEK293 cell expression system and enzymatically Biotin-labeled using AviTag™ technology.
- Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 20mM GSH and 20% glycerol.
- Unspsc Code: 12352202
- Unspsc Name: Proteins
- Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
- Product Type: Protein
- Concentration: 0.2 mg/ml
- Biosafety Level: Not applicable (BSL-1)
- Related Products: 40451, 40450, 75003, 78487
- Storage Stability: At least 6 months at -80°C. Storing diluted enzyme is not recommended, if necessary, use carrier protein (BSA 0.1 - 0.5%).
- Scientific Category: Kinase