DESCRIPTION

• Aa: full length
• Mw: 87 kDa
• Tags: N-terminal GST-tag
• Format: Aqueous buffer solution
• Genbank: NM_001003931
• Species: Human
• Uniprot: Q9Y6F1
• Shiptemp: -80°C (dry ice)
• Synonyms: poly (ADP-ribose) polymerase 3, poly(ADP-ribosyl)transferase 3, PARP3
• Warnings: Avoid freeze/thaw cycles.
• Category: PARP/Enzymes
• References: 1. Rouleau M., et al. J Cell Biochem. 2007 Feb 1;100(2):385-401.2. Augustin A., et al. J Cell Sci. 2003 Apr 15;116(Pt 8):1551-62. Application Reference(s): Fragment-based ligand design of novel potent inhibitors of tankyrases (2013)
• Description: Human PARP3 (GenBank Accession No. NM_001003931), full length with N-terminal GST-tag, MW = 87 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
• Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 3 mM DTT, and 20% glycerol
• Unspsc Code: 12352202
• Unspsc Name: Proteins
• Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. 
• Product Type: Protein
• Biosafety Level: Not applicable (BSL-1)
• Unit Definition: One unit of PARP incorporates 100 pmoles of poly(ADP) in 1 minute from NAD into the acid-insoluble form.
• Assay Conditions: Enzyme reaction is conducted using BPS's PARP3 Assay Kit (Catalog #80553) at room temperature for 1 hour.
• Related Products: 80553, 80507, 80506, 80501, 80521
• Storage Stability: At least 6 months at -80°C.
• Scientific Category: PARP