POU2F2 Antibody (N-term) Blocking peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 5452
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: POU2F2
Other Names: POU domain, class 2, transcription factor 2, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, Octamer-binding protein 2, Oct-2, Octamer-binding transcription factor 2, OTF-2, POU2F2, OCT2, OTF2
Availability: 2 weeks
Bio Background: POU2F2 is a transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter.
Bio References: Galetti, M., et al. Biochem. Pharmacol. 80(2):179-187(2010)Bailey, S.D., et al. Diabetes Care (2010) In press :Advani, A.S., et al. Leuk. Lymphoma 51(4):606-612(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Filipski, K.K., et al. Clin. Pharmacol. Ther. 86(4):396-402(2009)
Primary Accession: P09086
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP13842a was selected from the N-term region of POU2F2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.