SARS-CoV-2 (COVID-19) NSP7&NSP8 Protein, His Tag

DESCRIPTION

During the formation of the coronaviral replication/transcription complex, essential steps include processing of the conserved polyprotein nsp7-10 region by the main protease Mpro and subsequent complex formation of the released nsp's. Upon infecting host cells, coronaviruses assemble a multi-subunit RNA-synthesis complex of viral non-structural proteins (nsp) responsible for the replication and transcription of the viral genome. non-structural proteins 7 (NSP7) forms a hexadecamer with nsp8 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers.

DETAILS

Tag: C-6×His
Host: E. coli
Size: 1mg
Buffer: PBS, pH7.4
Format: Liquid
Purity: 95%
Source: SARS-CoV-2 NSP7&NSP8, His Tag (NS8-C5125) is expressed from E. coli cells. It contains AA Ser 1 - Gln 83 (NSP7) & Ala 1 - Gln 198 (NSP8) (Accession # YP_009725303.1 (NSP7) & YP_009725304.1 (NSP8)).
Storage: -70℃
Category: Viral Proteins
Molecule: NSP7 & NSP8
Accession: YP_009725303.1 (NSP7) & YP_009725304.1 (NSP8)
Conjugate: Unconjugated
Stability: ● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Exp Region: Ser 1 - Gln 83 (NSP7) & Ala 1 - Gln 198 (NSP8)
Package Size: 200ug*5
Characteristics: This protein carries a polyhistidine tag. The protein has a calculated MW of 32.1 kDa. The protein migrates as 28-32 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 32.1 kDa
Shipping Condition: Dry ice
Species Reactivity: SARS-CoV-2
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