• Aa: full length
• Mw: 44.3 kDa
• Tags: C-terminal His-tag
• Format: Aqueous buffer solution
• Genbank: NM_002755
• Species: Human
• Uniprot: Q02750
• Shiptemp: -80°C (dry ice)
• Synonyms: MAK1, MAP2K1, mitogen-activated protein kinase kinase 1, MKK1, MAPK/ERK Kinase 1
• Warnings: Avoid freeze/thaw cycles.
• Category: Kinase/Kinase Substrates
• References: 1. Smith,C.K. and Windsor,W.T. Biochemistry 46 (5), 1358-1367 (2007). 2. Burgermeister,E. et al. Mol. Cell. Biol. 27 (3), 803-817 (2007).
• Description: Human MEK1 (K97R) (GenBank Accession No. NM_002755), full length with lysine97 to arginine mutation and C-terminal His-tag, MW=44.3 kDa, expressed in E. coli. The K97R mutation prevents ATP binding, making the kinase inactive.
• Formulation: 45 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 10% glycerol, 200 mM imidazole, and 3 mM DTT.
• Unspsc Code: 12352202
• Unspsc Name: Proteins
• Applications: Useful as a substrate of cRAF (RAF1) and other kinases.
• Product Type: Protein
• Biosafety Level: Not applicable (BSL-1)
• Related Products: 40148, 40081, 40077, 40072, 78487
• Specific Activity: inactive
• Storage Stability: At least 6 months at -80°C.
• Scientific Category: Kinase/Substrate

DESCRIPTION