27219
BTB-1
Cayman Chemical
DESCRIPTION
A reversible Kif18A inhibitor (IC50 = 1.69 μM); selective for Kif18A over a panel of seven kinesins at 100 μM; inhibits Kif18A-dependent microtubule motility in a microtubule gliding assay at 100 μM; induces mitotic accumulation of HeLa cells
DETAILS
- Inchi: InChI=1S/C12H8ClNO4S/c13-9-6-7-12(11(8-9)14(15)16)19(17,18)10-4-2-1-3-5-10/h1-8H
- Purity: ≥98%
- Raptas: Product Type|Biochemicals|Microtubule Dynamics||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Cell Biology|Cytoskeleton & Motor Proteins
- Smiles: O=S(C1=CC=CC=C1)(C2=CC=C(Cl)C=C2[N+]([O-])=O)=O
- Inchikey: VZDUQPHKUBZMLW-UHFFFAOYSA-N
- Cas Number: 86030-08-2
- Formulation: A crystalline solid
- Storage Temp: -20
- Shipping Temp: -20
- Formula Markup: C12H8ClNO4S
- Formula Weight: 297.7
- Shelf Life Days: 1460