Human Tau-441 (K18, P301L) Protein, Tag Free (MALS verified)

DESCRIPTION

Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

DETAILS

Tag: Native
Host: E. coli
Size: 100ug
Buffer: 20 mM Tris, 150 mM NaCl, pH7.5
Format: Liquid
Purity: 95%
Source: Human Tau-441 (K18, P301L) Protein, Tag Free (TAU-H5118) is expressed from E. coli cells. It contains AA Gln 244 - Glu 372 (Accession # P10636-8 (P301L)).
Storage: -70℃
Category: Other Recombinant Proteins
Molecule: Tau
Conjugate: Unconjugated
Stability: ● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Exp Region: Gln 244 - Glu 372
Package Size: 100ug*1
Characteristics: This protein carries no "tag". The protein has a calculated MW of 13.8 kDa. The protein migrates as 14-15 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
Endotoxin Level: 0.1 EU per μg
Molecular Weight: 13.8 kDa
Shipping Condition: Dry ice
Species Reactivity: Human
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