TGIF2 Antibody (C-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 60436
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: TGIF2
Other Names: Homeobox protein TGIF2, 5'-TG-3'-interacting factor 2, TGF-beta-induced transcription factor 2, TGFB-induced factor 2, TGIF2
Availability: 2 weeks
Bio Background: The protein encoded by this gene is a DNA-binding homeoboxprotein and a transcriptional repressor. The encoded proteinappears to repress transcription by recruiting histone deacetylasesto TGF beta-responsive genes. This gene is amplified andoverexpressed in some ovarian cancers, and mutations in this genecan cause holoprosencephaly.
Bio References: Watanabe, T., et al. Jpn. J. Cancer Res. 93(10):1114-1122(2002)Deloukas, P., et al. Nature 414(6866):865-871(2001)Melhuish, T.A., et al. J. Biol. Chem. 276(34):32109-32114(2001)Imoto, I., et al. Biochem. Biophys. Res. Commun. 276(1):264-270(2000)
Primary Accession: Q9GZN2