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sc-390775 SAMPLE sc-390775

Promo Available Scientist.com Supplier

PMVK (H-9)

Santa Cruz Biotechnology

DESCRIPTION

mouse monoclonal IgG1; PMVK Antibody (H-9) is an IgG1 κ mouse monoclonal PMVK antibody (also designated PMVK antibody) that detects the PMVK protein of human origin by WB, IP, IF and ELISA. PMVK Antibody (H-9) is available as both the non-conjugated anti-PMVK antibody form, as well as multiple conjugated forms of anti-PMVK antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. PMVK (phosphomevalonate kinase), also known as PMK, PMKA, PMKASE or HUMPMK, is a 192 amino acid peroxisomal enzyme belonging to the nucleoside monophosphate (NMP) kinase family and is expressed in heart, liver, skeletal muscle, kidney, and pancreas with lower expression in brain, placenta and lung. Induced by sterol, PMVK participates in isopentenyl diphosphate biosynthesis via the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway. PMVK exists as a monomer and is encoded by a gene located on human chromosome 1, which houses over 3,000 genes and is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome.

DETAILS

  • Host: mouse
  • Type: Primary
  • Uniprot: Q15126
  • Clonality: Monoclonal
  • Conjugate: unconjugated
  • Applications: WB, IP, IF, ELISA
  • Human Gene Id: 10654
  • Protein Target: PMVK
  • Human Gene Name: PMVK
  • Species Reactivity: human

PROMOTION TERMS

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.