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E6202Hu

Human Solute Carrier Organic Anion Transporter Family Member 4C1, SLCO4C1 ELISA Kit

Bioassay Technology Laboratory

DESCRIPTION

Organic anion transporter, capable of transporting pharmacological substances such as digoxin, ouabain, thyroxine, methotrexate and cAMP. May participate in the regulation of membrane transport of ouabain. Involved in the uptake of the dipeptidyl peptidase-4 inhibitor sitagliptin and hence may play a role in its transport into and out of renal proximal tubule cells. May be involved in the first step of the transport pathway of digoxin and various compounds into the urine in the kidney. May be involved in sperm maturation by enabling directed movement of organic anions and compounds within or between cells. This ion-transporting process is important to maintain the strict epididymal homeostasis necessary for sperm maturation. May have a role in secretory functions since seminal vesicle epithelial cells are assumed to secrete proteins involved in decapacitation by modifying surface proteins to facilitate the acquisition of the ability to fertilize the egg.

DETAILS

  • GeneID: 353189
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 78,948
  • Synonyms: OATP4C1;OATP-H;OATP-M1;OATPX;Organic anion transporter M1;PRO2176;SLC21A20;SLCO4C1;Solute carrier family 21 member 20;Solute carrier organic anion transporter family member 4C1
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: SLCO4C1
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 7.14ng/L
  • Target Protein: SLCO4C1
  • Detection Range: 15-3000ng/L
  • Full Product Name: Solute carrier organic anion transporter family member 4C1
  • Standard Solution: 3200ng/L
  • UniProt Accession: Q6ZQN7