SNAP25 Antibody (Center) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 6616
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: SNAP25
Other Names: Synaptosomal-associated protein 25, SNAP-25, Super protein, SUP, Synaptosomal-associated 25 kDa protein, SNAP25, SNAP
Availability: 2 weeks
Bio Background: Synaptic vesicle membrane docking and fusion is mediatedby SNAREs (soluble N-ethylmaleimide-sensitive factor attachmentprotein receptors) located on the vesicle membrane (v-SNAREs) andthe target membrane (t-SNAREs). The assembled v-SNARE/t-SNAREcomplex consists of a bundle of four helices, one of which issupplied by v-SNARE and the other three by t-SNARE. For t-SNAREs onthe plasma membrane, the protein syntaxin supplies one helix andthe protein encoded by this gene contributes the other two.Therefore, this gene product is a presynaptic plasma membraneprotein involved in the regulation of neurotransmitter release. Twoalternative transcript variants encoding different protein isoformshave been described for this gene.
Bio References: Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)Greaves, J., et al. J. Biol. Chem. 285(32):24629-24638(2010)Oner, O., et al. J Atten Disord (2010) In press :Zhang, H., et al. Eur. J. Paediatr. Neurol. (2010) In press :Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Primary Accession: P60880