71130
B7-H2 (CD275, ICOSL), Fc fusion (Human) HiP™ Recombinant
BPS Bioscience
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DESCRIPTION
Human secreted B7 homolog 2 (B7-H2)-Fc fusion protein, also known as CD275, ICOSL, ICOSLG, and B7-related protein (B7RP), GenBank Accession No. NM_001283050, a.a 19-258 fused to human IgG1 Fc region (a.a. 100-330) and expressed in a HEK293 cell expression system. MW = 53.3 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.
DETAILS
- Aa: 19-258
- Mw: 53.3 kDa
- Tags: C-terminal Fc fusion (Human IgG1)
- Format: Aqueous buffer solution
- Genbank: NM_001283050
- Species: Human
- Uniprot: O75144
- Shiptemp: -80°C (dry ice)
- Synonyms: B7 homolog 2, CD275, ICOSL, ICOSLG, B7-related protein (B7RP)
- Warnings: Avoid freeze/thaw cycles.
- Category: Immunotherapy/Protein
- References: 1. Guillonneau, C., et al., Transplantation. 2005; 80(4): 546-554. 2. Fan, X., et al., J. Exp. Med. 2014; 211(4): 715-725.
- Description: Human secreted B7 homolog 2 (B7-H2)-Fc fusion protein, also known as CD275, ICOSL, ICOSLG, and B7-related protein (B7RP), GenBank Accession No. NM_001283050, a.a 19-258 fused to human IgG1 Fc region (a.a. 100-330) and expressed in a HEK293 cell expression system. MW = 53.3 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.
- Formulation: 40 mM Tris-HCl, pH 8.0. 110 mM NaCl, 2.2 mM KCl and 20% glycerol
- Unspsc Code: 12352202
- Unspsc Name: Proteins
- Applications: Useful for the study of protein binding interactions, screening inhibitors, and selectivity profiling.
- Product Type: Protein
- Biosafety Level: Not applicable (BSL-1)
- Related Products: 71148, 71144, 71179
- Storage Stability: At least 6 months at -80°C.
- Scientific Category: Immunotherapy