T75946
Lei-Dab7 TFA
TargetMol
DESCRIPTION
Lei-Dab7 TFA, a selective and high-affinity blocker of the K Ca 2.2 (SK2) channel with a dissociation constant (K d) of 3.8 nM, demonstrates over 200-fold selectivity for K Ca 2.2 compared to K Ca 2.1, K Ca 2.3, K Ca 3.1, K v, and Kir2.1. Furthermore, Lei-Dab7 TFA enhances theta-burst responses and long-term potentiation (LTP) in rat hippocampal slices in vitro.
DETAILS
- Purity: 98%
- Category: Compound
- Molecular Weight: 3506.08
- Molecular Formula: C143H237F3N46O41S6
Lead Time: 4 - 5 weeks
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