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Human Myosin Light Chain 3, MYL3 ELISA Kit

Bioassay Technology Laboratory


Myosin essential light chain (ELC), ventricular/cardiac isoform is a protein that in humans is encoded by the MYL3 gene. This cardiac ventricular/slow skeletal ELC isoform is distinct from that expressed in fast skeletal muscle (MYL1) and cardiac atrial muscle (MYL4). Ventricular ELC is part of the myosin molecule and is important in modulating cardiac muscle contraction. Studies have provided evidence for ELC as modulator of myosin crossbridge kinetics. Treating cardiac myofibrils with the lysine-rich N-terminal peptide (amino acids 5-14) evoked a supramaximal increase in cardiac myofibrillar MgATPase activity at submaximal calcium concentrations, and further studies demonstrated that this region of ELC modulates the affinity of myosin for actin.


  • GeneID: 4634
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 21,932
  • Synonyms: Cardiac myosin light chain 1;CMH8;CMLC1;MLC1SB;MLC1V;MLC-lV/sb;MYL3;Myosin light chain 1, slow-twitch muscle B/ventricular isoform;Myosin light chain 3;Ventricular myosin alkali light chain;Ventricular myosin light chain 1;Ventricular/slow twitch myosin alkali light chain;VLC1;VLCl
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: MYL3
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 12.93ng/L
  • Target Protein: MYL3
  • Detection Range: 20-4500ng/L
  • Full Product Name: Myosin Light Chain 3
  • Standard Solution: 4800ng/L
  • UniProt Accession: P08590