30-1907
Anti-CD62P / P-selectin Monoclonal Antibody (Clone:AK4)-Biotin Conjugated
Abeomics
DESCRIPTION
CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster.
DETAILS
- Gene: SELP
- App Id: FACS, IP, WB, ICC, Functional Assay
- Antigen: CD62P
- Gene Id: 6403
- Isotype: Mouse IgG1
- Clone Name: AK4
- Uniprot Id: P16109
- Host Animal: Mouse
- Clonality Id: Monoclonal
- Conjugate Id: Biotin
- Reactivity Id: Human, Non-Human Primates
- Alternative Name: SELP||GMRP||GRMP
- Storage Condition: Store at 2-8°C. Do not freeze.
- Immunogen Information: Human platelets
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