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sc-515742 SAMPLE sc-515742

Promo Available Scientist.com Supplier

MTP (C-1)

Santa Cruz Biotechnology

DESCRIPTION

mouse monoclonal IgG1; MTP Antibody (C-1) is an IgG1 κ mouse monoclonal MTP antibody (also designated MTP antibody, Microsomal Triglyceride Transfer Protein antibody, Microsomal Triglyceride Transfer Protein (Large Polypeptide 88kDa) antibody, or Microsomal Triglyceride Transfer Protein Large Subunit antibody) that detects the MTP protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. MTP Antibody (C-1) is available as both the non-conjugated anti-MTP antibody form, as well as multiple conjugated forms of anti-MTP antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Microsomal triglyceride transfer protein (MTP), catalyzes the transport of cholesteryl ester, triglyceride and phospholipid between phospholipid surfaces. MTP is a heterodimer consisting of MTP and PDI (protein disulfide isomerase). It is required for the secretion of plasma lipoproteins containing apolipoprotein b. It is negatively regulation by insulin and positively regulated by cholesterol. MTP, which localizes to the endoplasmic reticulum (ER), is expressed primarily in small intestine and liver, kidney, testis and ovary. It is not expressed in epithelial cells. Defects in the MTP gene can cause abetalipoproteinemia (ABL) which is an autosomal recessive lipoprotein metabolism disorder.

DETAILS

  • Host: mouse
  • Type: Primary
  • Uniprot: P55157
  • Clonality: Monoclonal
  • Conjugate: unconjugated
  • Applications: WB, IP, IF, IHC(P), ELISA
  • Human Gene Id: 4547
  • Mouse Gene Id: 17777
  • Protein Target: MTP
  • Human Gene Name: MTTP
  • Mouse Gene Name: Mttp
  • Species Reactivity: mouse, rat, human

PROMOTION TERMS

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.