RP01034
Recombinant Human LAIR-2/CD306 Protein
ABclonal
DESCRIPTION
Leukocyte-associated immunoglobulin-like receptor 2 ( LAIR2 ), also known as CD36, is a 131 amino acid protein containing one lg-like C2-type domain, making it a member of the Ig superfamily. When compared to LAIR-1, its transmembrane counterpart, it shares 83% aa identity across the signal sequence and extracellular domains, the two LAIR proteins are thought to have arisen from a common gene ancestor and appear to share similar adhesion profiles. LAIR2 is thought to be secreted and may help modulate mucosal tolerance. As a natural competitor for LAIR1, soluble LAIR2 prevents binding of human LAIR1 to collagens and LAIR1 cross-linking, thereby regulating its inhibitory potential. LAIR2 is thought to be secreted and may help modulate mucosal tolerance.
DETAILS
- Tag: C-His
- Source: HEK293 cells
- Gene Id: 3904
- Species: Human
- Lead Time: 3-5 weekdays
- Swiss Prot: Q6ISS4
- Research Areas: Immune Checkpoint,Bio-Markers & CD Antigens
- Alternative Names: LAIR2,CD306
Equivalent Items
| ... Loading