T6319
OSI-027
TargetMol
DESCRIPTION
OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, and more than 100-fold selectivity observed for mTOR than PI3Kα, PI3Kβ, PI3Kγ or DNA-PK. Phase 1.
DETAILS
- Cas: 936890-98-1
- Purity: 98%
- Smiles: NC=1C2=C(N=C(N2N=CN1)[C@H]3CC[C@H](C(O)=O)CC3)C=4NC=5C(C4)=CC=CC5OC
- Category: Compound
- Molecular Weight: 406.44
- Molecular Formula: C21H22N6O3
Lead Time: 4 - 5 weeks
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