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CLA-C5246-100ug CLA-C5246-1mg

Cynomolgus CLEC12A / MICL / CLL-1 Protein, His Tag

ACROBiosystems

DESCRIPTION

CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.

DETAILS

  • Tag: N-10×His
  • Host: HEK293
  • Size: 1mg
  • Buffer: PBS, pH7.4
  • Format: Powder
  • Purity: 90%
  • Source: Cynomolgus CLEC12A, His Tag (CLA-C5246) is expressed from human 293 cells (HEK293). It contains AA His 32 - Ala 232 (Accession # A0A2K5WXQ6-1).
  • Storage: -20℃
  • Category: Bio-Markers & CD Antigens
  • Molecule: CLEC12A
  • Conjugate: Unconjugated
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Exp Region: His 32 - Ala 232
  • Swiss-prot: A0A2K5WXQ6-1
  • Package Size: 250ug*4
  • Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 25.5 kDa. The protein migrates as 34-46 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Endotoxin Level: 1.0 EU per μg
  • Molecular Weight: 25.5 kDa
  • Shipping Condition: RT
  • Species Reactivity: Cynomolgus
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html