T1876
Kobe0065
TargetMol
DESCRIPTION
Kobe0065 is a novel and effective small-molecule compound that inhibits the Ras-Raf interaction by structure-based drug design (SBDD); it displays potent activity, competitively inhibiting the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM.
DETAILS
- Cas: 436133-68-5
- Purity: 100%
- Smiles: Cc1ccc(NC(=S)NNc2c(cc(cc2[N+]([O-])=O)C(F)(F)F)[N+]([O-])=O)cc1Cl
- Category: Compound
- Molecular Weight: 449.79
- Molecular Formula: C15H11ClF3N5O4S
Lead Time: < 1 week
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