E1578Hu
Human Hyaluronan Synthase 2, HAS2 ELISA Kit
Bioassay Technology Laboratory
DESCRIPTION
Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction and it is particularly responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells into mesenchymal cells, a process crucial for heart development. May also play a role in vasculogenesis. High molecular mass hyaluronan also play a role in early contact inhibition a process which stops cell growth when cells come into contact with each other or the extracellular matrix (By similarity).
DETAILS
- GeneID: 3037
- Species: Human
- Storage: 2-8ºC
- MASS(Da): 63,566
- Synonyms: HA Synthase 2;HAS 2;HAS2;Hyaluronan Synthase 2;Hyaluronate Synthase 2;Hyaluronic acid Synthase 2
- Assay Time: 1h 30m
- Assay Type: Sandwich
- Gene Names: HAS2
- Reactivity: Human
- Sample Type: Serum, plasma, cell culture supernates
- Sensitivity: 2.69ng/L
- Target Protein: HAS2
- Detection Range: 5-1000ng/L
- Full Product Name: Hyaluronan Synthase 2
- Standard Solution: 1280ng/L
- UniProt Accession: Q92819