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28370

NOD-IN-1

Cayman Chemical

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DESCRIPTION

An inhibitor of NOD-like receptors and a derivative of nodinitib-1; inhibits C12-iE-DAP-induced NF-ĸB activation in HEK-Blue cells expressing human recombinant NOD1 or NOD2 (IC50s = 5.74 and 6.45 µM, respectively).

DETAILS

  • Inchi: InChI=1S/C18H17NO4S/c1-3-23-18(20)17-12-14-6-4-5-7-16(14)19(17)24(21,22)15-10-8-13(2)9-11-15/h4-12H,3H2,1-2H3
  • Purity: ≥98%
  • Raptas: Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Immunology & Inflammation|Innate Immunity|Pattern Recognition
  • Smiles: O=C(OCC)C1=CC2=CC=CC=C2N1S(C3=CC=C(C)C=C3)(=O)=O
  • Inchikey: OJMOGUKIYRAILM-UHFFFAOYSA-N
  • Cas Number: 132819-92-2
  • Formulation: A crystalline solid
  • Storage Temp: -20
  • Shipping Temp: -20
  • Formula Markup: C18H17NO4S
  • Formula Weight: 343.4
  • Shelf Life Days: 1460