RP01366
Recombinant Human Fc-gamma RIII alpha/CD16a(F176V) Protein
ABclonal
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DESCRIPTION
This protein is a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. The protein is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia.
DETAILS
- Tag: C-His
- Source: HEK293 cells
- Gene Id: 2214(F176V)
- Species: Human
- Lead Time: 3-5 weekdays
- Swiss Prot: P08637
- Research Areas: Fc & Fc Receptor
- Alternative Names: CD16,CD16A,FCG3,FCGR3,FCGRIII,FCR-10,FCRIII,FCRIIIA,IGFR3,IMD20,FCGR3A
Equivalent Items
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