Animal-Free Recombinant Rat CNTF

DESCRIPTION

CNTF is a potent neural factor that was originally characterized as a vital factor for the survival of chick ciliary neurons in vitro. CNTF is also important for the survival of other neural cell types, including primary sensory neurons, motor neurons, basal forebrain neurons and type 2 astrocytes. CNTF is highly conserved across species and exhibits cross-species bioactivity. Recombinant Rat CNTF is synthesized as a 199 amino acid polypeptide (22.7 kDa) lacking a hydrophobic N-terminal signal for secretion.

DETAILS

Gene Id: 25707
Uniprot: P20294
Activity: Determined by its ability to stimulate proliferation of human TF-1 cells using a concentration range of 25.0-35.0 ng/ml.
Category: RUO Cytokines
Subcategory: Animal-Free Cytokines
Research Areas: Angiogenesis/Cardiovascular, Apoptosis, Bone, Skeletal, Cartilage, Diabetes/Weight Regulation, Immune System, Inflammation, Neurobiology, Stem Cells and Differentiation, Wound Healing
Alternative Names: Ciliary Neurotrophic Factor
Species of Origin: Rat
Expression System Source: E.coli