E6495Hu
Human Nitric Oxide Synthase-interacting Protein, NOSIP ELISA Kit
Bioassay Technology Laboratory
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DESCRIPTION
E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB (By similarity).
Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity (PubMed:11149895, PubMed:15548660, PubMed:16135813).
DETAILS
- GeneID: 51070
- Species: Human
- Storage: 2-8ºC
- MASS(Da): 33,172
- Synonyms: CGI-25;E3 ubiquitin-protein ligase NOSIP;eNOS-interacting protein;Nitric oxide Synthase-interacting protein;NOSIP;RING-type E3 ubiquitin transferase NOSIP
- Assay Time: 1h 30m
- Assay Type: Sandwich
- Gene Names: NOSIP
- Reactivity: Human
- Sample Type: Serum, plasma, cell culture supernates
- Sensitivity: 0.029ng/ml
- Target Protein: NOSIP
- Detection Range: 0.05-30ng/ml
- Full Product Name: Nitric Oxide Synthase-interacting Protein
- Standard Solution: 32ng/ml
- UniProt Accession: Q9Y314