21200
WYE-28
Cayman Chemical
DESCRIPTION
An inhibitor of mTOR (IC50 = 0.08 nM); selective for mTOR over PI3Kα (IC50 = 6 nM); inhibits cell growth in LNCaP cells (IC50 = <1 nM)
DETAILS
- Inchi: InChI=1S/C30H34N8O5/c1-42-30(41)37-12-10-24(11-13-37)38-28-25(18-31-38)27(36-14-16-43-17-15-36)34-26(35-28)21-4-8-23(9-5-21)33-29(40)32-22-6-2-20(19-39)3-7-22/h2-9,18,24,39H,10-17,19H2,1H3,(H2,32,33,40)
- Purity: ≥98%
- Raptas: Product Type|Biochemicals|Kinase Inhibitors|mTOR||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Signaling|PI3K/Akt/mTOR Signaling
- Smiles: O=C(OC)N(CC1)CCC1N2N=CC3=C(N4CCOCC4)N=C(C5=CC=C(NC(NC6=CC=C(CO)C=C6)=O)C=C5)N=C32
- Inchikey: DLIGFKRUAOAIBA-UHFFFAOYSA-N
- Cas Number: 1062172-60-4
- Formulation: A crystalline solid
- Storage Temp: -20
- Shipping Temp: -20
- Formula Markup: C30H34N8O5
- Formula Weight: 586.6
- Shelf Life Days: 1460
Equivalent Items
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