4804-MSM1-P0 4804-MSM1-P1 4804-MSM1-P1ABX
NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker) - CloneID - NGFR5
NeoBiotechnologies
DESCRIPTION
It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
DETAILS
- Host: Mouse
- Gene ID: 4804
- Uniprot: P08138
- Clone ID: NGFR5
- Clonality: Monoclonal
- Gene Name: NGFR
- Supplied As: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
- Applications: FLOW, IHC, IF
- Protein Target: NGFR
- Species Reactivity: Human, Monkey, Baboon, Cat, Rabbit, Ferret
- Storage Conditions: Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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