42-1340
Anti-HSP40, YDJ1 Monoclonal Antibody (Clone : 1G10.H8) - PerCP
Abeomics
DESCRIPTION
Human HSP40/DnaJ proteins comprise a large protein family, members of which feature the J domain (named after the bacterial DnaJ protein). The J-domain spans the first 75 N-terminal amino acids and is separated from the C-terminal by a glycine/phenylalanine-rich domain. There are two main types of HSP40; type 1 DNAJ proteins including HDJ2 and yeast YdjI; type II includes yeast Sis1 and human Hdj1. Whereas type I possesses a zinc finger domain which helps in the function of protein folding, type II does not.
Members of the HSP40/DnaJ family play diverse roles in many cellular processes, such as folding, translocation, degradation and assembly of multi-protein complexes. HSP40 stimulates the ATPase activity of HSP70 which in turn causes conformational changes of the unfolded proteins. The HSP40-HSP70-unfolded protein complex further binds to co-chaperones Hip, Hop and HSP90 which leads to protein folding, or components of protein degradation machinery CHIP and BAG-1.
DETAILS
- Gene: YDJ1
- App Id: WB,IP,ELISA
- Gene Id: 855661
- Isotype: Mouse IgG1 Kappa
- Clone Name: 1G10.H8
- Uniprot Id: P25491
- Host Animal: Mouse
- Clonality Id: Monoclonal
- Conjugate Id: PerCP
- Purification: Protein G Purified
- Reactivity Id: Yeast
- Product Content: 50% glycerol, 0.09% sodium azide
- Alternative Name: YDJ1||MAS5||YNL064C||N2418||YNL2418C
- Application Note: WB (1:2000); optimal dilutions for assays should be determined by the user.
- Storage Condition: Store the antibody at 4°C
- Immunogen Information: Full length protein yeast HSP40 (YDJ1)