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Bovine Acyl-CoA Desaturase, SCD ELISA Kit

Bioassay Technology Laboratory


Involved in the biosynthesis of highly unsaturated fatty acids (HUFA) from the essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3) precursors, acting as a fatty acyl-coenzyme A (CoA) desaturase that introduces a cis double bond at carbon 6 of the fatty acyl chain. Catalyzes the first and rate limiting step in this pathway which is the desaturation of LA (18:2n-6) and ALA (18:3n-3) into gamma-linoleate (GLA) (18:3n-6) and stearidonate (18:4n-3), respectively (By similarity). Subsequently, in the biosynthetic pathway of HUFA n-3 series, it desaturates tetracosapentaenoate (24:5n-3) to tetracosahexaenoate (24:6n-3), which is then converted to docosahexaenoate (DHA)(22:6n-3), an important lipid for nervous system function (By similarity). It can also desaturate (11E)-octadecenoate (trans-vaccenoate, a metabolite in the biohydrogenation pathway of LA and the predominant trans fatty acid in cow milk) at carbon 6 generating (6Z,11E)-octadecadienoate (By similarity). In addition to Delta-6 activity, this enzyme exhibits Delta-8 activity with slight biases toward n-3 fatty acyl-CoA substrates (By similarity).


  • GeneID: 521822
  • Species: Bovine
  • Storage: 2-8ºC
  • MASS(Da): 52,533
  • Synonyms: Acyl-CoA 6-desaturase;D6D;Delta(6 desaturase;Delta(6 fatty acid desaturase;Delta-6 desaturase;Fatty acid desaturase 2;SCD
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: FADS2
  • Reactivity: Bovine
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 9.81ng/L
  • Target Protein: SCD
  • Detection Range: 20-3800ng/L
  • Full Product Name: Acyl-CoA desaturase
  • Standard Solution: 4000ng/L
  • UniProt Accession: A4FV48