Anti-CD31 / PECAM-1 (Endothelial Cell Marker) Monoclonal Antibody(Clone: JC/70A)-CF488

DESCRIPTION

CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.

DETAILS

Gene: PECAM1
App Id: FACS,IF
Gene Id: 5175
Isotype: Mouse IgG1, kappa
Clone Name: JC/70A
Uniprot Id: P16284
Host Animal: Mouse
Clonality Id: Monoclonal
Conjugate Id: CF488
Reactivity Id: Human
Product Content: Antibody Purified from Bioreactor Concentrate by Protein A/G and conjµgated to various reporter molecules. Prepared in 10mM PBS with 0.05% BSA and 0.05% azide. Contact us if you require this Ab in a different format.
Alternative Name: EndoCAM; PECA1; Platelet Endothelial Cell Adhesion Molecule 1; GPIIA'
Application Note: Flow Cytometry (5ul per test per one million cells or 5ul per 100ul of whole blood);Immunofluorescence (1:50-1:100);
Storage Condition: Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous.
Immunogen Information: Membrane preparation of a spleen from a patient with hairy cell leukemia