RP01446
Recombinant Human TNFSF12/TWEAK Protein
ABclonal
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DESCRIPTION
TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue distribution. It can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. It is also found that TNFSF12 promotes proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. TNFSF12 also is a weak inducer of apoptosis in some cell types and mediates NF-kappa-B activation.
DETAILS
- Tag: No tag
- Source: E. coli
- Gene Id: 8742
- Species: Human
- Lead Time: 3-5 weekdays
- Swiss Prot: O43508-1
- Research Areas: Other Recombinant Protein
- Alternative Names: TNFSF12,APO3L,DR3LG,TNLG4A,TWEAK
Equivalent Items
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