Human NKG2C / CD159c Protein, His Tag

DESCRIPTION

Human NKG2C (NK cell Group 2 isoform C; Killer cell lectin-like receptor subfamily C, member 2) is a member of the C-type lectin-like superfamily of proteins. NKG2C plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. The CD94/NKG2C killer lectin-like receptor (KLR) specific for HLA-E is coupled to the KARAP/DAP12 adapter in a subset of NK cells, triggering their effector functions. CD94/NKG2C may operate as an alternative activation pathway for a subset of CD8+ T lymphocytes, triggering their effector functions and proliferation upon specific ligand engagement.

DETAILS

Tag: N-10×His
Host: HEK293
Size: 1mg
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Human NKG2C, His Tag (NKC-H5248) is expressed from human 293 cells (HEK293). It contains AA Ile 94 - Leu 231 (Accession # P26717-1).
Storage: -20℃
Category: Bio-Markers & CD Antigens
Molecule: NKG2C
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ile 94 - Leu 231
Swiss-prot: P26717-1
Package Size: 250ug*4
Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 17.8 kDa. The protein migrates as 30-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 17.8 kDa
Shipping Condition: RT
Species Reactivity: Human
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