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E6678Hu

Human Glycosylphosphatidylinositol-anchored High Density Lipoprotein Binding Protein 1, GPIHBP1 ELISA Kit

Bioassay Technology Laboratory

DESCRIPTION

Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries (By similarity). Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries (By similarity). Protects LPL against loss of activity, and against ANGPTL4-mediated unfolding (PubMed:27929370, PubMed:29899144). Thereby, plays an important role in lipolytic processing of chylomicrons by LPL, triglyceride metabolism and lipid homeostasis (PubMed:19304573, PubMed:21314738). Binds chylomicrons and phospholipid particles that contain APOA5 (PubMed:17997385, PubMed:19304573). Binds high-density lipoprotein (HDL) and plays a role in the uptake of lipids from HDL (By similarity).

DETAILS

  • GeneID: 338328
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 19,806
  • Synonyms: Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1;GPI-anchored HDL-binding protein 1;GPIHBP1;GPI-HBP1;High density lipoprotein-binding protein 1;HYPL1D
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: GPIHBP1
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 0.29ng/ml
  • Target Protein: GPIHBP1
  • Detection Range: 0.5-100ng/ml
  • Full Product Name: Glycosylphosphatidylinositol-anchored High Density Lipoprotein Binding Protein 1
  • Standard Solution: 128ng/ml
  • UniProt Accession: Q8IV16