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T71156

Poloxipan

TargetMol

- Open Babel Depiction S O N N CH 3 O N CH 3 Br O

DESCRIPTION

Poloxipan is a potent and pan-specific PLK1 inhibitor. In vitro, Poloxipan has IC50 3.2 uM (Plk1); 1.7 uM (Plk2); and 3 uM (Plk3). Poloxipan showed minor inhibition over FHA dommain of Chk2, S2 domian of STAT1, STAT5b, Lck, etc.

DETAILS

  • Cas: 1239513-63-3
  • Purity: 98%
  • Smiles: O=C\1N2C(S/C1=C\C3=C(OC)C=CC(Br)=C3)=NC(=O)C(C)=N2
  • Category: Compound
  • Molecular Weight: 380.22
  • Molecular Formula: C14H10BrN3O3S

Lead Time: Please Inquire

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