mouse monoclonal IgG2a; SR-1D Antibody (H-4) is an IgG2a κ mouse monoclonal SR-1D antibody (also designated 5HT1D antibody, 5-Hydroxytryptamine Receptor 1D antibody, 5-HT1D antibody, 5-Hydroxytryptamine (Serotonin) Receptor 1D antibody, G Protein-Coupled Serotonin 1D Alpha Receptor antibody, Serotonin Receptor 1D antibody, 5-HT-1D-Alpha antibody, 5-HT-1D antibody, HTR1DA antibody, HT1DA antibody, HTRL antibody, or RDC4 antibody) that detects the SR-1D protein of mouse, rat and human origin by WB, IP, IF and ELISA. SR-1D Antibody (H-4) is available as both the non-conjugated anti-SR-1D antibody form, as well as multiple conjugated forms of anti-SR-1D antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. beta-adrenergic bound to adrenaline activates adenylyl cyclase, while alpha2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the alpha2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-1-SR-7 (5HT1-5HT7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.