RP00111
Recombinant Human Erythropoietin R/EPO-R Protein
ABclonal
Image
Image
DESCRIPTION
This protein is erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
DETAILS
- Tag: C-hFc&His
- Source: HEK293 cells
- Gene Id: 2057
- Species: Human
- Lead Time: 3-5 weekdays
- Swiss Prot: P19235
- Research Areas: Cytokines & Cytokine receptors
- Alternative Names: EPOR,EPO-R
Equivalent Items
| ... Loading