Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) - CloneID - TYRP1/3280

DESCRIPTION

It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

DETAILS

Host: Mouse
Gene ID: 7306
Uniprot: P17643
Clone ID: TYRP1/3280
Clonality: Monoclonal
Gene Name: TYRP1
Supplied As: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Applications: IHC
Protein Target: TYRP1
Species Reactivity: Human
Storage Conditions: Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.