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42-1480-200

Scientist.com Supplier

Anti-HSP47 Monoclonal Antibody (Clone : 1C4-1A6) - APC

Abeomics

DESCRIPTION

HSP47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of HSP47 around fibrotic lesions. The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since HSP47 binds a single substrate. Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils.

DETAILS

  • Gene: SERPINH1
  • App Id: WB,ICC/IF
  • Gene Id: 871
  • Isotype: Mouse IgG1 Kappa
  • Clone Name: 1C4-1A6
  • Uniprot Id: P50454
  • Host Animal: Mouse
  • Clonality Id: Monoclonal
  • Conjugate Id: APC
  • Purification: Protein G Purified
  • Reactivity Id: Human
  • Product Content: PBS pH7.4, 50% glycerol, 0.09% sodium azide
  • Alternative Name: SERPINH1||CBP1||CBP2||HSP47||SERPINH2||PIG14
  • Application Note: WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
  • Categories Name 1: Antibodies
  • Categories Name 2: Cell Signalling
  • Storage Condition: Store the antibody at 4°C
  • Immunogen Information: Human HSP47, full length