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Anti-HSP47 Monoclonal Antibody (Clone : 1C4-1A6) - APC
Abeomics
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DESCRIPTION
HSP47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of HSP47 around fibrotic lesions.
The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since HSP47 binds a single substrate. Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils.
DETAILS
- Gene: SERPINH1
- App Id: WB,ICC/IF
- Gene Id: 871
- Isotype: Mouse IgG1 Kappa
- Clone Name: 1C4-1A6
- Uniprot Id: P50454
- Host Animal: Mouse
- Clonality Id: Monoclonal
- Conjugate Id: APC
- Purification: Protein G Purified
- Reactivity Id: Human
- Product Content: PBS pH7.4, 50% glycerol, 0.09% sodium azide
- Alternative Name: SERPINH1||CBP1||CBP2||HSP47||SERPINH2||PIG14
- Application Note: WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
- Categories Name 1: Antibodies
- Categories Name 2: Cell Signalling
- Storage Condition: Store the antibody at 4°C
- Immunogen Information: Human HSP47, full length
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