34616
Corylifol A
Cayman Chemical
DESCRIPTION
A flavonoid; inhibits CES2 activity (Ki = 0.62 µM) and induces ERα and ERβ transcriptional activation in reporter assays using HeLa cells from 0.1-10 µM; is cytotoxic to (IC50 = 13.5 µg/ml), and inhibits IL-6-induced STAT3 promoter activity in (IC50 = 0.81 µM in a reporter assay), Hep3B hepatocellular carcinoma cells
DETAILS
- Inchi: InChI=1S/C25H26O4/c1-16(2)5-4-6-17(3)7-8-19-13-18(9-12-23(19)27)22-15-29-24-14-20(26)10-11-21(24)25(22)28/h5,7,9-15,26-27H,4,6,8H2,1-3H3/b17-7+
- Purity: ≥98%
- Raptas: Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Cancer|Cell Death||Research Area|Cancer|Transcription Factors|STATs||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Estrogens & Progestins
- Smiles: O=C1C(C2=CC(C/C=C(C)/CC/C=C(C)\C)=C(C=C2)O)=COC3=CC(O)=CC=C31
- Inchikey: ZBHUUXLHDOUMKM-REZTVBANSA-N
- Cas Number: 775351-88-7
- Formulation: A solid
- Item Origin: Plant/Psoralea corylifolia
- Storage Temp: -20
- Shipping Temp: -20
- Formula Markup: C25H26O4
- Formula Weight: 390.5
- Shelf Life Days: 1460