SR401811
Ctdsp2 Mouse siRNA Oligo Duplex (Locus ID 52468)
Origene Technologies, Inc.
DESCRIPTION
Ctdsp2 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each
DETAILS
- Note: Single siRNA duplex (10nmol) can be ordered.
- Purity: HPLC purified
- Refseq: NM_001113470, NM_146012
- Status: 3 Weeks*
- Summary: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells (By similarity).[UniProtKB/Swiss-Prot Function]
- Category: RNAi
- Synonyms: AI586070; D10Ertd73e; OS-4; OS4; SCP2
- Sequences: Available with shipment
- Stability: One year from date of shipment when stored at -20°C.
- Components: Ctdsp2 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 52468)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml Need an individual siRNA?
- Uniprot Id: Q8BX07
- Availability: 3 Weeks
- Quality Control: Tested by ESI-MS
- Performance Guaranteed: OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).
- Number of Transfections: Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM).