sc-390324 SAMPLE sc-390324
Promo Available
Scientist.com Supplier
MRTF-A (G-8)
Santa Cruz Biotechnology
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DESCRIPTION
mouse monoclonal IgG2a; MRTF-A/MKL1 Antibody (G-8) is an IgG2a κ mouse monoclonal MRTF-A antibody that detects MRTF-A of mouse, rat and human origin by WB, IP, IF and ELISA. MRTF-A/MKL1 Antibody (G-8) is available as the non-conjugated anti-MRTF-A antibody form, as well as multiple conjugated forms of anti-MRTF-A antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF regulates the transient response of several muscle genes in response to growth factors and recruits accessory myogenic factors to activate these muscle genes. SRF is required for the formation of vertebrate mesoderm leading to the origin of the cardiovascular system. Myocardin, in association with SRF in cardiac muscle cells, activates cardiac muscle promoters. Myocardin-related transcription factor A (MRTF-A) interacts with SRF and stimulates its transcriptional activity.
DETAILS
- Host: mouse
- Type: Primary
- Uniprot: Q969V6
- Clonality: Monoclonal
- Conjugate: unconjugated
- Applications: WB, IP, IF, ELISA
- Human Gene Id: 57591
- Mouse Gene Id: 223701
- Protein Target: MRTF-A
- Human Gene Name: MKL1
- Mouse Gene Name: Mkl1
- Species Reactivity: mouse, rat, human
PROMOTION TERMS
Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.
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