Mouse TSC1 Blocking Peptide (C-term S1138)

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 64930
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: Tsc1
Other Names: Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1, Kiaa0243
Availability: 2 weeks
Bio Background: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
Primary Accession: Q9EP53